Składniki - dowody naukowe

Wysoką skuteczność składników DEEP WORK potwierdzają tysiące publikacji naukowych. W renomowanych bazach danych znajdują się recenzowane badania kliniczne i metaanalizy, które dokumentują ich działanie. Poniżej znajdziesz wybrane przykłady tych opracowań:

Functional and Therapeutic Potential of Cynara scolymus in Health Benefits
Chiara Porro, Tarek Benameur, Antonia Cianciulli, Mirco Vacca, Margherita Chiarini, Maria De Angelis, Maria Antonietta Panaro (March 2024) PMID: 30316534

Preventive effect of Artichoke (Cynara scolymus L.) in kidney dysfunction against high fat-diet induced obesity in rats
Maryem Ben Salem, Hanen Affes, Raouia Dhouibi, Slim Charfi, Mouna Turki, Serria Hammami, Fatma Ayedi, Zouheir Sahnoun, Khaled Mounir Zeghal, Kamilia Ksouda (Jun 2022) PMID: 31855072

Effects of artichoke (Cynara scolymus) polyphenolic extract on growth, antioxidants and some immune parameters in common carp (Cyprinus carpio)
Elham Kia, Seyed Hossein Hoseinifar, Mohammad Mazandarani, Valiollah Jafari, Roghieh Safari, Marina Paolucci (March 2025) PMID: 40098136

Protective activity of Cynara scolymus L. leaf extract against chemically induced complex genomic alterations in CHO cells
Laura Vicedo Jacociunas, Heloisa Helena Rodrigues de Andrade, Mauricio Lehmann, Larissa Wölfle Pedersini, Alexandre de Barros Falcão Ferraz, Juliana da Silva, Rafael Rodrigues Dihl (July 2013) PMID: 23830816

Saffron (Crocus sativus L.): A Source of Nutrients for Health and for the Treatment of Neuropsychiatric and Age-Related Diseases
Adil El Midaoui, Imen Ghzaiel, Dominique Vervandier-Fasseur, Mohamed Ksila, Amira Zarrouk, Thomas Nury, Farid Khallouki, Aboubaker El Hessni, Salama Ouazzani Ibrahimi (January 2022) PMID: 35276955

Crocus Sativus for Insomnia: A Systematic Review and Meta-Analysis
Mohd Puad Munirah, Mohd Noor Norhayati, Mohamad Noraini (September 2022) PMID: 36141931

Crocus sativus a natural food coloring and flavoring has potent anti-tumor properties
Zahra Khorasanchi, Mojtaba Shafiee, Farnoush Kermanshahi, Majid Khazaei, Mikhail Ryzhikov, Mohammad Reza Parizadeh, Behnoush Kermanshahi, Gordon A Ferns (April 2018) PMID: 29747750

Saffron (Crocus sativus) and its constituents for pain management: A review of current evidence
Ali Mohammad Pourbagher-Shahri, Fatemeh Forouzanfar (November 2023) PMID: 37528638

Neurotrophic and Neuroprotective Effects of Hericium erinaceus
Izabela Szućko-Kociuba, Alicja Trzeciak-Ryczek, Patrycja Kupnicka, Dariusz Chlubek (November 2023) PMID: 37958943

Therapeutic Potential of Hericium erinaceus for Depressive Disorder
Pit Shan Chong, Man-Lung Fung, Kah Hui Wong, Lee Wei Lim (December 2019) PMID: 31881712

Improvement of cognitive functions by oral intake of Hericium erinaceus
Yuusuke Saitsu, Akemi Nishide, Kenji Kikushima, Kuniyoshi Shimizu, Koichiro Ohnuki PMID: 31413233

Hericium erinaceus: an edible mushroom with medicinal values
Md Asaduzzaman Khan, Mousumi Tania, Rui Liu, Mohammad Mijanur Rahman PMID: 23735479

Tagetes erecta L.: A traditional medicine effective in inflammatory process treatment
Carlos Rafael Vaz, Larissa Benvenutti, Fernanda Capitânio Goldoni, Roberta Nunes, Gustavo Santin Schneiker, Gabriel Antunes Rosa, Keyla Furtado, , Nara Lins Meira Quintão, José Roberto Santin (July 2024) PMID: 38996948

Bioactive Properties of Tagetes erecta Edible Flowers: Polyphenol and Antioxidant Characterization and Therapeutic Activity against Ovarian Tumoral Cells and Caenorhabditis elegans Tauopathy
Lorenzo Rivas-García, Lara Crespo-Antolín, Tamara Y Forbes-Hernández, Jose M Romero-Márquez, María D Navarro-Hortal, Miguel Arredondo, Juan Llopis, José L Quiles, Cristina Sánchez-González (December 2023) PMID: 38203451

Ameliorative effects of Tagetes erecta Linn. flower against desiccation stress-induced dry eye symptoms in the mice model
Hyesook Lee, Hyun Hwangbo, Jin-Won Hyun, Jung-Hyun Shim, Sun-Hee Leem, Gi-Young Kim, Yung Hyun Choi (March 2024) PMID: 38716164

Differential activity of wheat antioxidant defense system and alterations in the accumulation of osmolytes at different developmental stages as influenced by marigold (Tagetes erecta L.) leachates
Rayees Ahmad Mir, Surendra Argal, Mohammad Abass Ahanger, Keshav Singh Jatav, Rajiv Mohan Agarwal (December 2022) PMID: 36531349

Implications of endophytic microbiota in Camellia sinensis: a review on current understanding and future insights
Hengtong Xie, Xiaoxiao Feng, Mengcen Wang, Yuefei Wang, Mukesh Kumar Awasthi, Ping Xu (December 2020) PMID: 32881650

Camellia sinensis: historical perspectives and future prospects
Salil H Patel PMID: 16236672

Hormonal regulation of health-promoting compounds in tea (Camellia sinensis L.)
Golam Jalal Ahammed, Xin Li (August 2022) PMID: 35785551

Physiological genetics, chemical composition, health benefits and toxicology of tea (Camellia sinensis L.) flower: A review
Dan Chen, Guijie Chen, Yi Sun, Xiaoxiong Zeng, Hong Ye (July 2024) PMID: 33233193

Pharmacological attributes of Bacopa monnieri extract: Current updates and clinical manifestation
Urooj Fatima, Sonam Roy, Shahnawaz Ahmad, Sabeeha Ali, Wafaa M Elkady, Ilyas Khan, Rana M Alsaffar, Mohd Adnan, Asimul Islam, Md Imtaiyaz Hassan (August 2022) PMID: 36061899

Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial
Carlo Calabrese, William L Gregory, Michael Leo, Dale Kraemer, Kerry Bone, Barry Oken (July 2008) PMID: 18611150

Neuroprotection with Bacopa monnieri-A review of experimental evidence
Vijayanna Tirumalapura Shalini, Sajjanar Jambappa Neelakanta, Jaideep Sitaram Sriranjini (March 2021) PMID: 33675463

Use of Bacopa monnieri in the Treatment of Dementia Due to Alzheimer Disease: Systematic Review of Randomized Controlled Trials
Aneesh Basheer, Ayush Agarwal, Biswamohan Mishra, Anu Gupta, Madakasira Vasantha Padma Srivastava, Richard Kirubakaran, Venugopalan Vishnu (August 2022) PMID: 35612544

A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue
Erik M Olsson, Bo von Schéele, Alexander G Panossian (November 2008) PMID: 19016404

Acute Rhodiola rosea intake can improve endurance exercise performance
Katrien De Bock, Bert O Eijnde, Monique Ramaekers, Peter Hespel (June 2024) PMID: 15256690

Extract of Rhodiola rosea radix reduces the level of C-reactive protein and creatinine kinase in the blood
M Abidov, S Grachev, R D Seifulla, T N Ziegenfuss (July 2024) PMID: 15514725

The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence
Emilija Ivanova Stojcheva, José Carlos Quintela (June 2022) PMID: 35745023

Piperine: A review of its biological effects
Iahtisham-Ul Haq, Muhammad Imran, Muhammad Nadeem, Tabussam Tufail, Tanweer A Gondal, Mohammad S Mubarak (September 2020) PMID: 32929825

Piperine and Its Role in Chronic Diseases
Giuseppe Derosa, Pamela Maffioli, Amirhossein Sahebkar PMID: 27671817

Piper nigrum Extract: Dietary Supplement for Reducing Mammary Tumor Incidence and Chemotherapy-Induced Toxicity
Nadeeya Mad-Adam, Siribhon Madla, Narissara Lailerd, Poonsit Hiransai, Potchanapond Graidist 
(May 2023) PMID: 37238871

Iron and Physical Activity: Bioavailability Enhancers, Properties of Black Pepper (Bioperine) and Potential Applications
Diego Fernández-Lázaro, Juan Mielgo-Ayuso, Alfredo Córdova Martínez, Jesús Seco-Calvo (June 2020) PMID: 32599787

Neuroprotective and Antioxidant Effect of Ginkgo biloba Extract Against AD and Other Neurological Disorders
Sandeep Kumar Singh, Saurabh Srivastav, Rudolph J Castellani, Germán Plascencia-Villa, George Perry (July 2019) PMID: 31376068

Hair-growth promoting effect and anti-inflammatory mechanism of Ginkgo biloba polysaccharides
Yingna Li, Yu Sheng, Jiuyue Liu, Guangyu Xu, Wanwen Yu, Qingwen Cui, Xuechun Lu, Peige Du, Liping An (October 2021) PMID: 34973721

Ginkgo biloba extract for age-related macular degeneration
Jennifer R Evans (January 2013) PMID: 23440785

Ginkgo biloba as an Alternative Medicine in the Treatment of Anxiety in Dementia and other Psychiatric Disorders
Sandeep Kumar Singh, George E Barreto, Gjumrakch Aliev, Valentina Echeverria (Jest tylko rok 2017) PMID: 27908257

Biotechnological interventions for the production of forskolin, an active compound from the medicinal plant, Coleus forskohlii
Pulukkunadu Thekkeveedu Roshni, Punchappady Devasya Rekha (March 2024) PMID: 38623169

Coleus forskohlii Extract Supplementation in Conjunction with a Hypocaloric Diet Reduces the Risk Factors of Metabolic Syndrome in Overweight and Obese Subjects: A Randomized Controlled Trial
Hayley L Loftus, Katie J Astell, Michael L Mathai, Xiao Q Su (November 2015) PMID: 26593941

Extracts of Coleus forskohlii relieves cough and asthma symptoms via modulating inflammation and the extracellular matrix
Chaozhi Ma, Liyuan Zou, Yu Xia, Yijun Tu, Daquan Xue, Yanfang Yang, Dan Liu, Yanwen Liu, Hezhen Wu, Hanxiong Dan, Pengtao You (December 2018) PMID: 30520122

Plectranthus ecklonii Benth: A Comprehensive Review Into its Phytochemistry and Exerted Biological Activities
Ana Ribeirinha Antão, Gabrielle Bangay, Eva María Domínguez-Martín, Ana María Díaz-Lanza, Patrícia Ríjo (November 2021)

Fish oil supplementation alters the plasma lipidomic profile and increases long-chain PUFAs of phospholipids and triglycerides in healthy subjects
Inger Ottestad, Sahar Hassani, Grethe I Borge, Achim Kohler, Gjermund Vogt, Tuulia Hyötyläinen, Matej Orešič, Kirsti W Brønner, Kirsten B Holven, Stine M Ulven, Mari C W Myhrstad (August 2012) PMID: 22952598

The substrate specificities of sunflower and soybean phospholipases D using transphosphatidylation reaction
Slim Abdelkafi, Abdelkarim Abousalham (November 2011) PMID: 22044447

Influence of Long-Chain/Medium-Chain Triglycerides and Whey Protein/Tween 80 Ratio on the Stability of Phosphatidylserine Emulsions (O/W)
Ning Zhang, Chunhong Liu, Li Jin, Ruiyan Zhang, Hans-Christian Siebert, Zhengping Wang, Sangeeta Prakash, Xiaohan Yin, Jing Li, Danping Hou, Bin Sun, Min Liu (April 2020) PMID: 32309688

Production of a High-Phosphatidylserine Lecithin That Synergistically Inhibits Lipid Oxidation with α-Tocopherol in Oil-in-Water Emulsions
Harshika Arora, Mitch D Culler, Eric A Decker (March 2022) PMID: 35407101

Pantothenic acid in health and disease
A G Tahiliani, C J Beinlich PMID: 1746161

Bioavailability of pantothenic acid
H van den Berg (January 1997) PMID: 9023484

Pantothenic acid deficiency induced in human subjects
W B BEAN, R E HODGES, K DAUM PMID: 14392222

Pantothenic acid - a scoping review for Nordic Nutrition Recommendations 2023
Riitta Freese, Tonje E Aarsland, Maja Bjørkevoll (December 2023) PMID: 38187802

High-dose Vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression
David T Field, Rebekah O Cracknell, Jessica R Eastwood, Peter Scarfe, Claire M Williams, Ying Zheng, Teresa Tavassoli (July 2022) PMID: 35851507

Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial
Lionel Noah, Louise Dye, Béatrice Bois De Fer, André Mazur, Gisèle Pickering, Etienne Pouteau (May 2021) PMID: 33864354

Vitamin B6 metabolism in microbes and approaches for fermentative production
Jonathan Rosenberg, Till Ischebeck, Fabian M Commichau (November 2016) PMID: 27890703

Vitamin B6: a molecule for human health?
Hanjo Hellmann, Sutton Mooney (January 2010) PMID: 20110903

Pharmacokinetic comparisons of two acetyl-L-carnitine formulations in healthy Korean volunteers
Sang-Min Baek, Renhua Zheng, Eun-Jung Seo, Dae-Yeon Hwang, Bo-Hyung Kim (November 2015) PMID: 26396135

Metabolism and disposition of intravenously administered acetyl-L-carnitine in healthy volunteers
A Marzo, E Arrigoni Martelli, R Urso, M Rocchetti, V Rizza, J G Kelly PMID: 2591464

Effect of acetyl-L-carnitine on leukemia L1210 resistant to mitoxantrone
M Niang, M Mĕlka PMID: 11294129

L-acetylcarnitine as a new therapeutic approach for peripheral neuropathies with pain
M Onofrj, T Fulgente, D Melchionda, A Marchionni, F Tomasello, F M Salpietro, C Alafaci, E De Sanctis, G Pennisi, R Bella, PMID: 7490173

The Promise of Niacin in Neurology
Emily Wuerch, Gloria Roldan Urgoiti, V Wee Yong (April 2023) PMID: 37084148

Novel Niacin Receptor Agonists: A Promising Strategy for the Treatment of Dyslipidemia
Prajakta B Kothawade, Asha B Thomas, Sohan S Chitlange PMID: 33550969

Niacin-respondent subset of schizophrenia – a therapeutic review
X J Xu, G S Jiang PMID: 25855923

Niacin in cardiovascular prevention: mechanisms, efficacy, and safety
John R Guyton (August 2007) PMID: 17620858

Vascular benefits of vitamin C supplementation against fine particulate air pollution in healthy adults: A double-blind randomised crossover trial
Jingyi Ren, Jufeng Liang, Jiaqi Wang, Bowen Yin, Fan Zhang, Xiang Li, Siqi Zhu, Hao Tian, Qiqi Cui, Jianshi Song, Gang Liu, Wenhua Ling, Yuxia Ma (June 2022) PMID: 35689890

Vitamin C Supplementation and Athletic Performance: A Review
Dylan R Rogers, Denis J Lawlor, James L Moeller (July 2023) PMID: 37417662

Vitamin C intake and multiple health outcomes: an umbrella review of systematic reviews and meta-analyses
Kedi Xu, Rui Peng, Yuanlin Zou, Xiaoru Jiang, Qiuyu Sun, Chunhua Song (March 2022) PMID: 35291895

Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance
M Levine, C Conry-Cantilena, Y Wang, R W Welch, P W Washko, K R Dhariwal, J B Park, A Lazarev, J F Graumlich, J King, L R Cantilena (April 1996) PMID: 8623000

Potential Role of Vitamin D for the Management of Depression and Anxiety
Gleicilaine A S Casseb, Manuella P Kaster, Ana Lúcia S Rodrigues (July 2019) PMID: 31093951

The effect of vitamin D supplementation on the muscle damage after eccentric exercise in young men: a randomized, control trial
W Pilch, B Kita, A Piotrowska, Ł Tota, M Maciejczyk, O Czerwińska-Ledwig, E Sadowska-Krepa, S Kita, T Pałka (November 2020) PMID: 33176796

The effect of vitamin D supplementation on the muscle damage after eccentric exercise in young men: a randomized, control trial
W Pilch, B Kita, A Piotrowska, Ł Tota, M Maciejczyk, O Czerwińska-Ledwig, E Sadowska-Krepa , S Kita, T Pałka (November 2020) PMID: 33176796

Effects of Vitamin D Supplementation on Muscle Strength in Athletes: A Systematic Review
Chien-Ming Chiang, Ahmed Ismaeel, Rachel B Griffis, Suzy Weems (February 2017) PMID: 27379960

Endogenous metabolites promote stress resistance through induction of mitohormesis
Fabian Fischer, Michael Ristow (April 2020) PMID: 32329201

NALT M cells are important for immune induction for the common mucosal immune system
Yasuhiro Date, Masashi Ebisawa, Shinji Fukuda, Hideaki Shima, Yuuki Obata, Daisuke Takahashi, Tamotsu Kato, Misaho Hanazato, Gaku Nakato, Ifor R Williams, Koji Hase, Hiroshi Ohno (December 2017) PMID: 29186424

Nasal lymphoid tissue (NALT) as a mucosal immune inductive site
H Y Wu, H H Nguyen, M W Russell (November 1997) PMID: 9393634

Cytokine profile of NALT during acute stress and its possible effect on IgA secretion
Juan Manuel Gutiérrez-Meza, Rosa Adriana Jarillo-Luna, Victor Rivera-Aguilar, Angel Miliar-García, Rafael Campos-Rodríguez (August 2017) PMID: 28472640

Functional Role of Taurine in Aging and Cardiovascular Health: An Updated Overview
Gaetano Santulli, Urna Kansakar, Fahimeh Varzideh, Pasquale Mone, Stanislovas S Jankauskas, Angela Lombardi (September 2023) PMID: 37836520

Protective role of taurine against oxidative stress (Review)
Stella Baliou, Maria Adamaki, Petros Ioannou, Aglaia Pappa, Mihalis I Panayiotidis, Demetrios A Spandidos, Ioannis Christodoulou, Anthony M Kyriakopoulos, Vassilis Zoumpourlis (June 2021) PMID: 34184084

Taurine linked with healthy aging
Joseph McGaunn, Joseph A Baur (June 2023) PMID: 37289872

Taurine in development
J A Sturman (October 1988) PMID: 3054019

Citicoline for treating people with acute ischemic stroke
Arturo J Martí-Carvajal, Claudia Valli, Cristina Elena Martí-Amarista, Ivan Solà, Joan Martí-Fàbregas, Xavier Bonfill Cos (August 2020) PMID: 32860632

Unveiling citicoline's mechanisms and clinical relevance in the treatment of neuroinflammatory disorders
Simona Cavalu, Sameh Saber, Asmaa Ramadan, Elsayed A Elmorsy, Rabab S Hamad, Mustafa Ahmed Abdel-Reheim, Mahmoud E Youssef (September 2024) PMID: 39221499

Citicoline - a neuroprotector with proven effects on glaucomatous disease
Chitu Iulia, Tudosescu Ruxandra, Leasu-Branet Costin, Voinea Liliana-Mary (July 2017) PMID: 29450391

Citicoline mechanisms and clinical efficacy in cerebral ischemia
Rao Muralikrishna Adibhatla, J F Hatcher (October 2002) PMID: 12271462

Coenzyme Q10 supplementation: Efficacy, safety, and formulation challenges
Marta Arenas-Jal, J M Suñé-Negre, Encarna García-Montoya (February 2020) PMID: 33325173

Disorders of Human Coenzyme Q10 Metabolism: An Overview
Iain Hargreaves, Robert A Heaton, David Mantle (September 2020) PMID: 32933108

Coenzyme Q10 for heart failure
Tareq Al Saadi, Yazan Assaf, Medhat Farwati, Khaled Turkmani, Ahmed Al-Mouakeh, Baraa Shebli, Mohammed Khoja, Adib Essali, Mohammed E Madmani (February 2021) PMID: 35608922

Does Coenzyme Q10 Supplementation Improve Human Oocyte Quality?
Cristina Rodríguez-Varela, Elena Labarta (September 2021) PMID: 34502447

Ion-exclusion chromatography determination of organic acid in uridine 5'-monophosphate fermentation broth
Huanqing Niu, Yong Chen, Jingjing Xie, Xiaochun Chen, Jianxin Bai, Jinglan Wu, Dong Liu, Hanjie Ying (May 2012) PMID: 22634191

Structural and functional characterization of cyclic pyrimidine-regulated anti-phage system
Mei-Hui Hou, Chao-Jung Chen, Chia-Shin Yang, Yu-Chuan Wang, Yeh Chen (July 2024) PMID: 38965224

Orotidine 5'-Monophosphate Decarboxylase: The Operation of Active Site Chains Within and Across Protein Subunits
Tiago A S Brandão, John P Richard (May 2020) PMID: 32374983

A potent, covalent inhibitor of orotidine 5'-monophosphate decarboxylase with antimalarial activity
Angelica M Bello, Ewa Poduch, Masahiro Fujihashi, Merhnaz Amani, Yan Li, Ian Crandall, Raymond Hui, Ping I Lee, Kevin C Kain, Emil F Pai, Lakshmi P Kotra (February 2007) PMID: 17290979

Role of Thiamin in Health and Disease
Bertha F Polegato, Amanda G Pereira, Paula S Azevedo, Nara A Costa, Leonardo A M Zornoff, Sergio A R Paiva, Marcos F Minicucci (January 2019) PMID: 30644592

Thiamine mimetics sulbutiamine and benfotiamine as a nutraceutical approach to anticancer therapy
Hunter C Jonus, Charnel C Byrnes, Jaeah Kim, Maria L Valle, Michael G Bartlett, Hamid M Said, Jason A Zastre (November 2019) PMID: 31810115

Thiamin(e): the spark of life
Derrick Lonsdale PMID: 22116701

Thiamin status and cognitive impairment in the elderly
J D Kanofsky (June 1996) PMID: 8935434

Vitamin B12 deficiency - A 21st century perspective
Michael J Shipton, Jecko Thachil (April 2015) PMID: 25824066

Vitamin B12 in meat and dairy products
Doreen Gille, Alexandra Schmid (February 2015) PMID: 26024497

Bioavailability of vitamin B12
Lindsay Helen Allen (October 2010) PMID: 21462117

The spectrum of vitamin B12 deficiency
G L Clementz, S G Schade (January 1990) PMID: 2278533

Ekstrakt z liści karczocha zwyczajnego (Cynara scolymus)

Functional and Therapeutic Potential of Cynara scolymus in Health Benefits
Chiara Porro, Tarek Benameur, Antonia Cianciulli, Mirco Vacca, Margherita Chiarini, Maria De Angelis, Maria Antonietta Panaro (March 2024) PMID: 30316534

Preventive effect of Artichoke (Cynara scolymus L.) in kidney dysfunction against high fat-diet induced obesity in rats
Maryem Ben Salem, Hanen Affes, Raouia Dhouibi, Slim Charfi, Mouna Turki, Serria Hammami, Fatma Ayedi, Zouheir Sahnoun, Khaled Mounir Zeghal, Kamilia Ksouda (Jun 2022) PMID: 31855072

Effects of artichoke (Cynara scolymus) polyphenolic extract on growth, antioxidants and some immune parameters in common carp (Cyprinus carpio)
Elham Kia, Seyed Hossein Hoseinifar, Mohammad Mazandarani, Valiollah Jafari, Roghieh Safari, Marina Paolucci (March 2025) PMID: 40098136

Protective activity of Cynara scolymus L. leaf extract against chemically induced complex genomic alterations in CHO cells
Laura Vicedo Jacociunas, Heloisa Helena Rodrigues de Andrade, Mauricio Lehmann, Larissa Wölfle Pedersini, Alexandre de Barros Falcão Ferraz, Juliana da Silva, Rafael Rodrigues Dihl (July 2013) PMID: 23830816

Ekstrakt z kwiatów szafranu uprawnego (Crocus sativus)

Saffron (Crocus sativus L.): A Source of Nutrients for Health and for the Treatment of Neuropsychiatric and Age-Related Diseases
Adil El Midaoui, Imen Ghzaiel, Dominique Vervandier-Fasseur, Mohamed Ksila, Amira Zarrouk, Thomas Nury, Farid Khallouki, Aboubaker El Hessni, Salama Ouazzani Ibrahimi (January 2022) PMID: 35276955

Crocus Sativus for Insomnia: A Systematic Review and Meta-Analysis
Mohd Puad Munirah, Mohd Noor Norhayati, Mohamad Noraini (September 2022) PMID: 36141931

Crocus sativus a natural food coloring and flavoring has potent anti-tumor properties
Zahra Khorasanchi, Mojtaba Shafiee, Farnoush Kermanshahi, Majid Khazaei, Mikhail Ryzhikov, Mohammad Reza Parizadeh, Behnoush Kermanshahi, Gordon A Ferns (April 2018) PMID: 29747750

Saffron (Crocus sativus) and its constituents for pain management: A review of current evidence
Ali Mohammad Pourbagher-Shahri, Fatemeh Forouzanfar (November 2023) PMID: 37528638

Ekstrakt z owocników soplówki jeżowatej (Hericium erinaceus)

Neurotrophic and Neuroprotective Effects of Hericium erinaceus
Izabela Szućko-Kociuba, Alicja Trzeciak-Ryczek, Patrycja Kupnicka, Dariusz Chlubek (November 2023) PMID: 37958943

Therapeutic Potential of Hericium erinaceus for Depressive Disorder
Pit Shan Chong, Man-Lung Fung, Kah Hui Wong, Lee Wei Lim (December 2019) PMID: 31881712

Improvement of cognitive functions by oral intake of Hericium erinaceus
Yuusuke Saitsu, Akemi Nishide, Kenji Kikushima, Kuniyoshi Shimizu, Koichiro Ohnuki PMID: 31413233

Hericium erinaceus: an edible mushroom with medicinal values
Md Asaduzzaman Khan, Mousumi Tania, Rui Liu, Mohammad Mijanur Rahman PMID: 23735479

Ekstrakt z kwiatów aksamitki wzniesionej (Tagetes erecta)

Tagetes erecta L.: A traditional medicine effective in inflammatory process treatment
Carlos Rafael Vaz, Larissa Benvenutti, Fernanda Capitânio Goldoni, Roberta Nunes, Gustavo Santin Schneiker, Gabriel Antunes Rosa, Keyla Furtado, , Nara Lins Meira Quintão, José Roberto Santin (July 2024) PMID: 38996948

Bioactive Properties of Tagetes erecta Edible Flowers: Polyphenol and Antioxidant Characterization and Therapeutic Activity against Ovarian Tumoral Cells and Caenorhabditis elegans Tauopathy
Lorenzo Rivas-García, Lara Crespo-Antolín, Tamara Y Forbes-Hernández, Jose M Romero-Márquez, María D Navarro-Hortal, Miguel Arredondo, Juan Llopis, José L Quiles, Cristina Sánchez-González (December 2023) PMID: 38203451

Ameliorative effects of Tagetes erecta Linn. flower against desiccation stress-induced dry eye symptoms in the mice model
Hyesook Lee, Hyun Hwangbo, Jin-Won Hyun, Jung-Hyun Shim, Sun-Hee Leem, Gi-Young Kim, Yung Hyun Choi (March 2024) PMID: 38716164

Differential activity of wheat antioxidant defense system and alterations in the accumulation of osmolytes at different developmental stages as influenced by marigold (Tagetes erecta L.) leachates
Rayees Ahmad Mir, Surendra Argal, Mohammad Abass Ahanger, Keshav Singh Jatav, Rajiv Mohan Agarwal (December 2022) PMID: 36531349

Ekstrakt z liści herbaty chińskiej (Camellia sinensis)

Implications of endophytic microbiota in Camellia sinensis: a review on current understanding and future insights
Hengtong Xie, Xiaoxiao Feng, Mengcen Wang, Yuefei Wang, Mukesh Kumar Awasthi, Ping Xu (December 2020) PMID: 32881650

Camellia sinensis: historical perspectives and future prospects
Salil H Patel PMID: 16236672

Hormonal regulation of health-promoting compounds in tea (Camellia sinensis L.)
Golam Jalal Ahammed, Xin Li (August 2022) PMID: 35785551

Physiological genetics, chemical composition, health benefits and toxicology of tea (Camellia sinensis L.) flower: A review
Dan Chen, Guijie Chen, Yi Sun, Xiaoxiong Zeng, Hong Ye (July 2024) PMID: 33233193

Ekstrakt z ziela bakopy drobnolistnej (Bacopa monnieri)

Pharmacological attributes of Bacopa monnieri extract: Current updates and clinical manifestation
Urooj Fatima, Sonam Roy, Shahnawaz Ahmad, Sabeeha Ali, Wafaa M Elkady, Ilyas Khan, Rana M Alsaffar, Mohd Adnan, Asimul Islam, Md Imtaiyaz Hassan (August 2022) PMID: 36061899

Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial
Carlo Calabrese, William L Gregory, Michael Leo, Dale Kraemer, Kerry Bone, Barry Oken (July 2008) PMID: 18611150

Neuroprotection with Bacopa monnieri-A review of experimental evidence
Vijayanna Tirumalapura Shalini, Sajjanar Jambappa Neelakanta, Jaideep Sitaram Sriranjini (March 2021) PMID: 33675463

Use of Bacopa monnieri in the Treatment of Dementia Due to Alzheimer Disease: Systematic Review of Randomized Controlled Trials
Aneesh Basheer, Ayush Agarwal, Biswamohan Mishra, Anu Gupta, Madakasira Vasantha Padma Srivastava, Richard Kirubakaran, Venugopalan Vishnu (August 2022) PMID: 35612544

Ekstrakt z korzenia różeńca górskiego (Rhodiola rosea)

A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue
Erik M Olsson, Bo von Schéele, Alexander G Panossian (November 2008) PMID: 19016404

Acute Rhodiola rosea intake can improve endurance exercise performance
Katrien De Bock, Bert O Eijnde, Monique Ramaekers, Peter Hespel (June 2024) PMID: 15256690

Extract of Rhodiola rosea radix reduces the level of C-reactive protein and creatinine kinase in the blood
M Abidov, S Grachev, R D Seifulla, T N Ziegenfuss (July 2024) PMID: 15514725

The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence
Emilija Ivanova Stojcheva, José Carlos Quintela (June 2022) PMID: 35745023

Ekstrakt z owoców pieprzu czarnego (Piper nigrum)

Piperine: A review of its biological effects
Iahtisham-Ul Haq, Muhammad Imran, Muhammad Nadeem, Tabussam Tufail, Tanweer A Gondal, Mohammad S Mubarak (September 2020) PMID: 32929825

Piperine and Its Role in Chronic Diseases
Giuseppe Derosa, Pamela Maffioli, Amirhossein Sahebkar PMID: 27671817

Piper nigrum Extract: Dietary Supplement for Reducing Mammary Tumor Incidence and Chemotherapy-Induced Toxicity
Nadeeya Mad-Adam, Siribhon Madla, Narissara Lailerd, Poonsit Hiransai, Potchanapond Graidist 
(May 2023) PMID: 37238871

Iron and Physical Activity: Bioavailability Enhancers, Properties of Black Pepper (Bioperine) and Potential Applications
Diego Fernández-Lázaro, Juan Mielgo-Ayuso, Alfredo Córdova Martínez, Jesús Seco-Calvo (June 2020) PMID: 32599787

Ekstrakt z liści miłorzębu dwuklapowego (Ginkgo biloba)

Neuroprotective and Antioxidant Effect of Ginkgo biloba Extract Against AD and Other Neurological Disorders
Sandeep Kumar Singh, Saurabh Srivastav, Rudolph J Castellani, Germán Plascencia-Villa, George Perry (July 2019) PMID: 31376068

Hair-growth promoting effect and anti-inflammatory mechanism of Ginkgo biloba polysaccharides
Yingna Li, Yu Sheng, Jiuyue Liu, Guangyu Xu, Wanwen Yu, Qingwen Cui, Xuechun Lu, Peige Du, Liping An (October 2021) PMID: 34973721

Ginkgo biloba extract for age-related macular degeneration
Jennifer R Evans (January 2013) PMID: 23440785

Ginkgo biloba as an Alternative Medicine in the Treatment of Anxiety in Dementia and other Psychiatric Disorders
Sandeep Kumar Singh, George E Barreto, Gjumrakch Aliev, Valentina Echeverria (Jest tylko rok 2017) PMID: 27908257

Ekstrakt z korzeni pokrzywy indyjskiej (Coleus forskohlii)

Biotechnological interventions for the production of forskolin, an active compound from the medicinal plant, Coleus forskohlii
Pulukkunadu Thekkeveedu Roshni, Punchappady Devasya Rekha (March 2024) PMID: 38623169

Coleus forskohlii Extract Supplementation in Conjunction with a Hypocaloric Diet Reduces the Risk Factors of Metabolic Syndrome in Overweight and Obese Subjects: A Randomized Controlled Trial
Hayley L Loftus, Katie J Astell, Michael L Mathai, Xiao Q Su (November 2015) PMID: 26593941

Extracts of Coleus forskohlii relieves cough and asthma symptoms via modulating inflammation and the extracellular matrix
Chaozhi Ma, Liyuan Zou, Yu Xia, Yijun Tu, Daquan Xue, Yanfang Yang, Dan Liu, Yanwen Liu, Hezhen Wu, Hanxiong Dan, Pengtao You (December 2018) PMID: 30520122

Plectranthus ecklonii Benth: A Comprehensive Review Into its Phytochemistry and Exerted Biological Activities
Ana Ribeirinha Antão, Gabrielle Bangay, Eva María Domínguez-Martín, Ana María Díaz-Lanza, Patrícia Ríjo (November 2021)

Fosfatydyloseryna słonecznikowa

Fish oil supplementation alters the plasma lipidomic profile and increases long-chain PUFAs of phospholipids and triglycerides in healthy subjects
Inger Ottestad, Sahar Hassani, Grethe I Borge, Achim Kohler, Gjermund Vogt, Tuulia Hyötyläinen, Matej Orešič, Kirsti W Brønner, Kirsten B Holven, Stine M Ulven, Mari C W Myhrstad (August 2012) PMID: 22952598

The substrate specificities of sunflower and soybean phospholipases D using transphosphatidylation reaction
Slim Abdelkafi, Abdelkarim Abousalham (November 2011) PMID: 22044447

Influence of Long-Chain/Medium-Chain Triglycerides and Whey Protein/Tween 80 Ratio on the Stability of Phosphatidylserine Emulsions (O/W)
Ning Zhang, Chunhong Liu, Li Jin, Ruiyan Zhang, Hans-Christian Siebert, Zhengping Wang, Sangeeta Prakash, Xiaohan Yin, Jing Li, Danping Hou, Bin Sun, Min Liu (April 2020) PMID: 32309688

Production of a High-Phosphatidylserine Lecithin That Synergistically Inhibits Lipid Oxidation with α-Tocopherol in Oil-in-Water Emulsions
Harshika Arora, Mitch D Culler, Eric A Decker (March 2022) PMID: 35407101

Kwas pantotenowy

Pantothenic acid in health and disease
A G Tahiliani, C J Beinlich PMID: 1746161

Bioavailability of pantothenic acid
H van den Berg (January 1997) PMID: 9023484

Pantothenic acid deficiency induced in human subjects
W B BEAN, R E HODGES, K DAUM PMID: 14392222

Pantothenic acid - a scoping review for Nordic Nutrition Recommendations 2023
Riitta Freese, Tonje E Aarsland, Maja Bjørkevoll (December 2023) PMID: 38187802

Witamina B6

High-dose Vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression
David T Field, Rebekah O Cracknell, Jessica R Eastwood, Peter Scarfe, Claire M Williams, Ying Zheng, Teresa Tavassoli (July 2022) PMID: 35851507

Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial
Lionel Noah, Louise Dye, Béatrice Bois De Fer, André Mazur, Gisèle Pickering, Etienne Pouteau (May 2021) PMID: 33864354

Vitamin B6 metabolism in microbes and approaches for fermentative production
Jonathan Rosenberg, Till Ischebeck, Fabian M Commichau (November 2016) PMID: 27890703

Vitamin B6: a molecule for human health?
Hanjo Hellmann, Sutton Mooney (January 2010) PMID: 20110903

Chlorowodorek acetylo L-karnityny (ALCAR HCl)

Pharmacokinetic comparisons of two acetyl-L-carnitine formulations in healthy Korean volunteers
Sang-Min Baek, Renhua Zheng, Eun-Jung Seo, Dae-Yeon Hwang, Bo-Hyung Kim (November 2015) PMID: 26396135

Metabolism and disposition of intravenously administered acetyl-L-carnitine in healthy volunteers
A Marzo, E Arrigoni Martelli, R Urso, M Rocchetti, V Rizza, J G Kelly PMID: 2591464

Effect of acetyl-L-carnitine on leukemia L1210 resistant to mitoxantrone
M Niang, M Mĕlka PMID: 11294129

L-acetylcarnitine as a new therapeutic approach for peripheral neuropathies with pain
M Onofrj, T Fulgente, D Melchionda, A Marchionni, F Tomasello, F M Salpietro, C Alafaci, E De Sanctis, G Pennisi, R Bella, PMID: 7490173

Niacyna

The Promise of Niacin in Neurology
Emily Wuerch, Gloria Roldan Urgoiti, V Wee Yong (April 2023) PMID: 37084148

Novel Niacin Receptor Agonists: A Promising Strategy for the Treatment of Dyslipidemia
Prajakta B Kothawade, Asha B Thomas, Sohan S Chitlange PMID: 33550969

Niacin-respondent subset of schizophrenia – a therapeutic review
X J Xu, G S Jiang PMID: 25855923

Niacin in cardiovascular prevention: mechanisms, efficacy, and safety
John R Guyton (August 2007) PMID: 17620858

Witamina C

Vascular benefits of vitamin C supplementation against fine particulate air pollution in healthy adults: A double-blind randomised crossover trial
Jingyi Ren, Jufeng Liang, Jiaqi Wang, Bowen Yin, Fan Zhang, Xiang Li, Siqi Zhu, Hao Tian, Qiqi Cui, Jianshi Song, Gang Liu, Wenhua Ling, Yuxia Ma (June 2022) PMID: 35689890

Vitamin C Supplementation and Athletic Performance: A Review
Dylan R Rogers, Denis J Lawlor, James L Moeller (July 2023) PMID: 37417662

Vitamin C intake and multiple health outcomes: an umbrella review of systematic reviews and meta-analyses
Kedi Xu, Rui Peng, Yuanlin Zou, Xiaoru Jiang, Qiuyu Sun, Chunhua Song (March 2022) PMID: 35291895

Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance
M Levine, C Conry-Cantilena, Y Wang, R W Welch, P W Washko, K R Dhariwal, J B Park, A Lazarev, J F Graumlich, J King, L R Cantilena (April 1996) PMID: 8623000

Witamina D

Potential Role of Vitamin D for the Management of Depression and Anxiety
Gleicilaine A S Casseb, Manuella P Kaster, Ana Lúcia S Rodrigues (July 2019) PMID: 31093951

The effect of vitamin D supplementation on the muscle damage after eccentric exercise in young men: a randomized, control trial
W Pilch, B Kita, A Piotrowska, Ł Tota, M Maciejczyk, O Czerwińska-Ledwig, E Sadowska-Krepa, S Kita, T Pałka (November 2020) PMID: 33176796

The effect of vitamin D supplementation on the muscle damage after eccentric exercise in young men: a randomized, control trial
W Pilch, B Kita, A Piotrowska, Ł Tota, M Maciejczyk, O Czerwińska-Ledwig, E Sadowska-Krepa , S Kita, T Pałka (November 2020) PMID: 33176796

Effects of Vitamin D Supplementation on Muscle Strength in Athletes: A Systematic Review
Chien-Ming Chiang, Ahmed Ismaeel, Rachel B Griffis, Suzy Weems (February 2017) PMID: 27379960

N-acetylo L-tyrozyna (NALT)

Endogenous metabolites promote stress resistance through induction of mitohormesis
Fabian Fischer, Michael Ristow (April 2020) PMID: 32329201

NALT M cells are important for immune induction for the common mucosal immune system
Yasuhiro Date, Masashi Ebisawa, Shinji Fukuda, Hideaki Shima, Yuuki Obata, Daisuke Takahashi, Tamotsu Kato, Misaho Hanazato, Gaku Nakato, Ifor R Williams, Koji Hase, Hiroshi Ohno (December 2017) PMID: 29186424

Nasal lymphoid tissue (NALT) as a mucosal immune inductive site
H Y Wu, H H Nguyen, M W Russell (November 1997) PMID: 9393634

Cytokine profile of NALT during acute stress and its possible effect on IgA secretion
Juan Manuel Gutiérrez-Meza, Rosa Adriana Jarillo-Luna, Victor Rivera-Aguilar, Angel Miliar-García, Rafael Campos-Rodríguez (August 2017) PMID: 28472640

Tauryna

Functional Role of Taurine in Aging and Cardiovascular Health: An Updated Overview
Gaetano Santulli, Urna Kansakar, Fahimeh Varzideh, Pasquale Mone, Stanislovas S Jankauskas, Angela Lombardi (September 2023) PMID: 37836520

Protective role of taurine against oxidative stress (Review)
Stella Baliou, Maria Adamaki, Petros Ioannou, Aglaia Pappa, Mihalis I Panayiotidis, Demetrios A Spandidos, Ioannis Christodoulou, Anthony M Kyriakopoulos, Vassilis Zoumpourlis (June 2021) PMID: 34184084

Taurine linked with healthy aging
Joseph McGaunn, Joseph A Baur (June 2023) PMID: 37289872

Taurine in development
J A Sturman (October 1988) PMID: 3054019

Cytokolina

Citicoline for treating people with acute ischemic stroke
Arturo J Martí-Carvajal, Claudia Valli, Cristina Elena Martí-Amarista, Ivan Solà, Joan Martí-Fàbregas, Xavier Bonfill Cos (August 2020) PMID: 32860632

Unveiling citicoline's mechanisms and clinical relevance in the treatment of neuroinflammatory disorders
Simona Cavalu, Sameh Saber, Asmaa Ramadan, Elsayed A Elmorsy, Rabab S Hamad, Mustafa Ahmed Abdel-Reheim, Mahmoud E Youssef (September 2024) PMID: 39221499

Citicoline - a neuroprotector with proven effects on glaucomatous disease
Chitu Iulia, Tudosescu Ruxandra, Leasu-Branet Costin, Voinea Liliana-Mary (July 2017) PMID: 29450391

Citicoline mechanisms and clinical efficacy in cerebral ischemia
Rao Muralikrishna Adibhatla, J F Hatcher (October 2002) PMID: 12271462

Koenzym Q10

Coenzyme Q10 supplementation: Efficacy, safety, and formulation challenges
Marta Arenas-Jal, J M Suñé-Negre, Encarna García-Montoya (February 2020) PMID: 33325173

Disorders of Human Coenzyme Q10 Metabolism: An Overview
Iain Hargreaves, Robert A Heaton, David Mantle (September 2020) PMID: 32933108

Coenzyme Q10 for heart failure
Tareq Al Saadi, Yazan Assaf, Medhat Farwati, Khaled Turkmani, Ahmed Al-Mouakeh, Baraa Shebli, Mohammed Khoja, Adib Essali, Mohammed E Madmani (February 2021) PMID: 35608922

Does Coenzyme Q10 Supplementation Improve Human Oocyte Quality?
Cristina Rodríguez-Varela, Elena Labarta (September 2021) PMID: 34502447

Monofosforan urydyny

Ion-exclusion chromatography determination of organic acid in uridine 5'-monophosphate fermentation broth
Huanqing Niu, Yong Chen, Jingjing Xie, Xiaochun Chen, Jianxin Bai, Jinglan Wu, Dong Liu, Hanjie Ying (May 2012) PMID: 22634191

Structural and functional characterization of cyclic pyrimidine-regulated anti-phage system
Mei-Hui Hou, Chao-Jung Chen, Chia-Shin Yang, Yu-Chuan Wang, Yeh Chen (July 2024) PMID: 38965224

Orotidine 5'-Monophosphate Decarboxylase: The Operation of Active Site Chains Within and Across Protein Subunits
Tiago A S Brandão, John P Richard (May 2020) PMID: 32374983

A potent, covalent inhibitor of orotidine 5'-monophosphate decarboxylase with antimalarial activity
Angelica M Bello, Ewa Poduch, Masahiro Fujihashi, Merhnaz Amani, Yan Li, Ian Crandall, Raymond Hui, Ping I Lee, Kevin C Kain, Emil F Pai, Lakshmi P Kotra (February 2007) PMID: 17290979

Tiamina

Role of Thiamin in Health and Disease
Bertha F Polegato, Amanda G Pereira, Paula S Azevedo, Nara A Costa, Leonardo A M Zornoff, Sergio A R Paiva, Marcos F Minicucci (January 2019) PMID: 30644592

Thiamine mimetics sulbutiamine and benfotiamine as a nutraceutical approach to anticancer therapy
Hunter C Jonus, Charnel C Byrnes, Jaeah Kim, Maria L Valle, Michael G Bartlett, Hamid M Said, Jason A Zastre (November 2019) PMID: 31810115

Thiamin(e): the spark of life
Derrick Lonsdale PMID: 22116701

Thiamin status and cognitive impairment in the elderly
J D Kanofsky (June 1996) PMID: 8935434

Witamina B12

Vitamin B12 deficiency - A 21st century perspective
Michael J Shipton, Jecko Thachil (April 2015) PMID: 25824066

Vitamin B12 in meat and dairy products
Doreen Gille, Alexandra Schmid (February 2015) PMID: 26024497

Bioavailability of vitamin B12
Lindsay Helen Allen (October 2010) PMID: 21462117

The spectrum of vitamin B12 deficiency
G L Clementz, S G Schade (January 1990) PMID: 2278533